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  1. Chemokine signals and their cell-surface receptors are important modulators of HIV-1 disease and cancer. To aid future case/control association studies, aim to further characterise the haplotype structure of v...

    Authors: Vanessa J Clark and Michael Dean

    Citation: Human Genomics 2004 1:195

    Content type: Primary research

    Published on:

  3. Genome comparisons are behind the powerful new annotation methods being developed to find all human genes, as well as genes from other genomes. Genomes are now frequently being studied in pairs to provide cros...

    Authors: David R. Nelson and Daniel W. Nebert

    Citation: Human Genomics 2004 1:146

    Content type: Genome update

    Published on:

  5. Global gene expression analysis is beginning to move from the laboratories of basic investigators to large-scale clinical trials. The potential of this technology to improve diagnosis and tailored treatment of...

    Authors: Kristen M. Carr, Kevin Rosenblatt, Emanuel F. Petricoin and Lance A. Liotta

    Citation: Human Genomics 2004 1:134

    Content type: Review

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  6. The finding, during the last decade, that several common, clinically delineated syndromes are caused by submicroscopic deletions or, more rarely, by duplications, has provided a powerful tool in the annotation...

    Authors: Koen Devriendt and Joris R. Vermeesch

    Citation: Human Genomics 2004 1:126

    Content type: Review

    Published on:

  7. The genetic basis for most of the rare lipid monogenic disorders have been elucidated, but the challenge remains in determining the combination of genes that contribute to the genetic variability in lipid leve...

    Authors: Jose M. Ordovas

    Citation: Human Genomics 2004 1:111

    Content type: Review

    Published on:

  8. The genetic dissection of complex disease remains a significant challenge. Sample-tracking and the recording, processing and storage of high-throughput laboratory data with public domain data, require integrat...

    Authors: Oliver S. Burren, Barry C. Healy, Alex C. Lam, Helen Schuilenburg, Geoffrey E. Dolman, Vincent H. Everett, Davide Laneri, Sarah Nutland, Helen E. Rance, Felicity Payne, Deborah Smyth, Chris Lowe, Bryan J. Barratt, Rebecca C.J. Twells, Daniel B. Rainbow, Linda S. Wicker…

    Citation: Human Genomics 2004 1:98

    Content type: Primary research

    Published on:

  9. In this paper, data on 20 X-chromosomal microsatellite polymorphisms from the HGDP-CEPH cell line panel are used to infer human population structure. Inferences from these data are compared to those obtained f...

    Authors: Sohini Ramachandran, Noah A. Rosenberg, Lev A. Zhivotovsky and Marcus W. Feldman

    Citation: Human Genomics 2004 1:87

    Content type: Primary research

    Published on:

  13. There is now a wide choice of software available for linkage analysis. The most well known packages are briefly reviewed here. The package with the most extensive range of analyses is GENEHUNTER, but for many ...

    Authors: Frank Dudbridge

    Citation: Human Genomics 2003 1:63

    Content type: Software review

    Published on:

  16. Rapidly developing comparative gene maps in selected mammal species are providing an opportunity to reconstruct the genomic architecture of mammalian ancestors and study rearrangements that transformed this an...

    Authors: William J Murphy, Guillaume Bourque, Glenn Tesler, Pavel Pevzner and Stephen J O'Brien

    Citation: Human Genomics 2003 1:30

    Content type: Primary research

    Published on:

  17. In the search for genetic determinants of complex disease, two approaches to association analysis are most often employed, testing single loci or testing a small group of loci jointly via haplotypes for their ...

    Authors: Xiaohua Zhang, Kathryn Roeder, Garrick Wallstrom and Bernie Devlin

    Citation: Human Genomics 2003 1:20

    Content type: Primary research

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Human Genomics

ISSN: 1479-7364

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