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Table 2 Expression analysis of risk genes in AD cases and controls using AlzData database

From: Convergent lines of evidence support BIN1 as a risk gene of Alzheimer’s disease

Gene Entorhinal cortex Hippocampus Temporal cortex Frontal cortex
FC P FDR FC P FDR FC P FDR FC P FDR
CR1 0.23 0.071 0.197 − 0.01 0.896 0.954 0.39 0.033 0.118 − 0.04 0.655 0.906
BIN1 − 0.12 0.265 0.452 − 0.26 0.002 0.028 − 0.09 0.458 0.67 0.11 0.13 0.268
HLA-DRA 0.46 0.042 0.142 NA NA NA NA NA NA NA NA NA
  1. We investigated whether the identified risk genes are differentially expressed in AD patients compared to controls, using a comprehensive database AlzData (http://www.alzdata.org/). FC fold change, FDR false discovery rate, NA not available
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Human Genomics

ISSN: 1479-7364

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